4D6D

Crystal structure of a family 98 glycoside hydrolase catalytic module (Sp3GH98) in complex with the blood group A-trisaccharide (X02 mutant)

4D6D の概要

• エントリーDOI: 10.2210/pdb4d6d/pdb
• 関連するPDBエントリー: 4D6C 4D6E 4D6F 4D6G 4D6H 4D6I 4D6J
• 分子名称: GLYCOSIDE HYDROLASE, alpha-L-fucopyranose-(1-2)-[2-acetamido-2-deoxy-alpha-D-galactopyranose-(1-3)]beta-D-galactopyranose, 1,2-ETHANEDIOL, ... (4 entities in total)
• 機能のキーワード: hydrolase, glycoside hydrolase, blood group antigen
• 由来する生物種: STREPTOCOCCUS PNEUMONIAE
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 69809.30

構造登録者

Kwan, D.H.,Constantinescu, I.,Chapanian, R.,Higgins, M.A.,Samain, E.,Boraston, A.B.,Kizhakkedathu, J.N.,Withers, S.G. (登録日: 2014-11-11, 公開日: 2014-11-26, 最終更新日: 2023-12-20)

• 主引用文献: Kwan, D.H.,Constantinescu, I.,Chapanian, R.,Higgins, M.A.,Koetzler, M.,Samain, E.,Boraston, A.B.,Kizhakkedathu, J.N.,Withers, S.G.; Towards Efficient Enzymes for the Generation of Universal Blood Through Structure-Guided Directed Evolution.; J.Am.Chem.Soc., 137:5695-, 2015; PubMed: 25870881; DOI: 10.1021/JA5116088

実験手法

X-RAY DIFFRACTION (1.52 Å)