4D1T
High resolution structure of native tVIM-7 from Pseudomonas aeruginosa
Summary for 4D1T
Entry DOI | 10.2210/pdb4d1t/pdb |
Related | 4D1U 4D1V 4D1W |
Descriptor | METALLO-B-LACTAMASE, ZINC ION (3 entities in total) |
Functional Keywords | hydrolase, residue determinants, ligand interaction |
Biological source | PSEUDOMONAS AERUGINOSA |
Total number of polymer chains | 1 |
Total formula weight | 28263.69 |
Authors | Leiros, H.-K.S.,Skagseth, S.,Edvardsen, K.S.W.,Lorentzen, M.S.,Bjerga, G.E.K.,Leiros, I.,Samuelsen, O. (deposition date: 2014-05-05, release date: 2014-06-25, Last modification date: 2023-12-20) |
Primary citation | Leiros, H.-K.S.,Skagseth, S.,Edvardsen, K.S.W.,Lorentzen, M.S.,Bjerga, G.E.K.,Leiros, I.,Samuelsen, O. His224 Alters the R2 Drug Binding Site and Phe218 Influences the Catalytic Efficiency in the Metallo-Beta-Lactamase Vim-7. Antimicrob.Agents Chemother., 58:4826-, 2014 Cited by PubMed: 24913158DOI: 10.1128/AAC.02735-13 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.25 Å) |
Structure validation
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