4D0L

Phosphatidylinositol 4-kinase III beta-PIK93 in a complex with Rab11a- GTP gammaS

4D0L の概要

• エントリーDOI: 10.2210/pdb4d0l/pdb
• 関連するPDBエントリー: 4D0M
• 分子名称: PHOSPHATIDYLINOSITOL 4-KINASE BETA, RAS-RELATED PROTEIN RAB-11A, N-(5-(4-CHLORO-3-(2-HYDROXY-ETHYLSULFAMOYL)- PHENYLTHIAZOLE-2-YL)-ACETAMIDE, ... (6 entities in total)
• 機能のキーワード: transferase-hydrolase complex, transferase, phosphatidylinositol 4-kinase, pi4k, nucleotide, gtp, rab11, pik93, signaling, gtpase, signal transduction, golgi, recycling endosome, pi4p, phosphoinositide, ptdins4p, pi4kb, transferase/hydrolase
• 由来する生物種: HOMO SAPIENS (HUMAN); 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 270715.16

構造登録者

Burke, J.E.,Inglis, A.J.,Perisic, O.,Masson, G.R.,McLaughin, S.H.,Rutaganira, F.,Shokat, K.M.,Williams, R.L. (登録日: 2014-04-29, 公開日: 2014-05-28, 最終更新日: 2023-12-20)

• 主引用文献: Burke, J.E.,Inglis, A.J.,Perisic, O.,Masson, G.R.,Mclaughlin, S.H.,Rutaganira, F.,Shokat, K.M.,Williams, R.L.; Structures of Pi4Kiiibeta Complexes Show Simultaneous Recruitment of Rab11 and its Effectors.; Science, 344:1035-, 2014; PubMed: 24876499; DOI: 10.1126/SCIENCE.1253397

実験手法

X-RAY DIFFRACTION (2.94 Å)