4D0K
Complex of Chaetomium thermophilum PAN2 (WD40-CS1) with PAN3 (C-term)
Summary for 4D0K
| Entry DOI | 10.2210/pdb4d0k/pdb |
| Related | 4CZV 4CZW 4CZX 4CZY |
| Descriptor | A-SPECIFIC RIBONUCLEASE SUBUNIT PAN2, PAB-DEPENDENT POLY(A)-SPECIFIC RIBONUCLEASE SUBUNIT PAN3-LIKE PROTEIN (3 entities in total) |
| Functional Keywords | gene regulation, wd40 domain, c-terminal knob domain, deadenylation, mrna decay, pan2-pan3 complex |
| Biological source | CHAETOMIUM THERMOPHILUM More |
| Total number of polymer chains | 3 |
| Total formula weight | 82441.18 |
| Authors | Jonas, S.,Izaurralde, E.,Weichenrieder, O. (deposition date: 2014-04-28, release date: 2014-06-04, Last modification date: 2023-12-20) |
| Primary citation | Jonas, S.,Christie, M.,Peter, D.,Bhandari, D.,Loh, B.,Huntzinger, E.,Weichenrieder, O.,Izaurralde, E. An Asymmetric Pan3 Dimer Recruits a Single Pan2 Exonuclease to Mediate Mrna Deadenylation and Decay. Nat.Struct.Mol.Biol., 21:599-, 2014 Cited by PubMed: 24880343DOI: 10.1038/NSMB.2837 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.89 Å) |
Structure validation
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