4CWA

Structure of Plasmodium Falciparum Spermidine Synthase in Complex with 1H-Benzimidazole-2-pentanamine

4CWA の概要

• エントリーDOI: 10.2210/pdb4cwa/pdb
• 分子名称: SPERMIDINE SYNTHASE, 5-(1H-benzimidazol-2-yl)pentan-1-amine, 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, ... (4 entities in total)
• 機能のキーワード: transferase, aminopropyl transferase, polyamine pathway, rossmann-like fold
• 由来する生物種: PLASMODIUM FALCIPARUM
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 97322.32

構造登録者

Sprenger, J.,Halander, J.C.,Svensson, B.,Al-Karadaghi, S.,Persson, L. (登録日: 2014-04-01, 公開日: 2014-10-08, 最終更新日: 2023-12-20)

• 主引用文献: Sprenger, J.,Svensson, B.,Halander, J.,Carey, J.,Persson, L.,Al-Karadaghi, S.; Three-Dimensional Structures of Plasmodium Falciparum Spermidine Synthase with Bound Inhibitors Suggest New Strategies for Drug Design.; Acta Crystallogr.,Sect.D, 71:484-, 2015; PubMed: 25760598; DOI: 10.1107/S1399004714027011

実験手法

X-RAY DIFFRACTION (2.02 Å)