4CW6
Crystal structure of cofactor-free urate oxidase in complex with the 5-peroxo derivative of 9-metyl uric acid (X-ray dose, 92 kGy)
Summary for 4CW6
Entry DOI | 10.2210/pdb4cw6/pdb |
Related | 4CW0 4CW2 4CW3 |
Descriptor | URICASE, (5S)-5-(dioxidanyl)-9-methyl-7H-purine-2,6,8-trione, (4S)-2-METHYL-2,4-PENTANEDIOL, ... (6 entities in total) |
Functional Keywords | oxidoreductase, cofactor-free oxidase |
Biological source | ASPERGILLUS FLAVUS |
Cellular location | Peroxisome: Q00511 |
Total number of polymer chains | 1 |
Total formula weight | 34746.03 |
Authors | Bui, S.,Steiner, R.A. (deposition date: 2014-04-01, release date: 2014-10-29, Last modification date: 2018-02-21) |
Primary citation | Bui, S.,von Stetten, D.,Jambrina, P.G.,Prange, T.,Colloc'h, N.,de Sanctis, D.,Royant, A.,Rosta, E.,Steiner, R.A. Direct evidence for a peroxide intermediate and a reactive enzyme-substrate-dioxygen configuration in a cofactor-free oxidase. Angew. Chem. Int. Ed. Engl., 53:13710-13714, 2014 Cited by PubMed: 25314114DOI: 10.1002/anie.201405485 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.28 Å) |
Structure validation
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