4CVG

Structure of bovine endothelial nitric oxide synthase heme domain (H4B-free) supplemented with 50uM Zn acetate and with poor binding of 6-acetyl-2-amino-7,7-dimethyl-7,8-dihydropteridin-4(3H)-one.

4CVG の概要

• エントリーDOI: 10.2210/pdb4cvg/pdb
• 関連するPDBエントリー: 4CUL 4CUM 4CUN
• 分子名称: NITRIC OXIDE SYNTHASE, ENDOTHELIAL, ARGININE, PROTOPORPHYRIN IX CONTAINING FE, ... (7 entities in total)
• 機能のキーワード: oxidoreductase, cofactor analog complex
• 由来する生物種: BOS TAURUS (CATTLE)
• 細胞内の位置: Cell membrane: P29473
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 101313.01

構造登録者

Chreifi, G.,Li, H.,Poulos, T.L. (登録日: 2014-03-25, 公開日: 2014-05-28, 最終更新日: 2014-07-16)

• 主引用文献: Chreifi, G.,Li, H.,Mcinnes, C.R.,Gibson, C.L.,Suckling, C.J.,Poulos, T.L.; Communication between the Zinc and Tetrahydrobiopterin Binding Sites in Nitric Oxide Synthase.; Biochemistry, 53:4216-, 2014; PubMed: 24819538; DOI: 10.1021/BI5003986

実験手法

X-RAY DIFFRACTION (2.31 Å)