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4COO

Crystal structure of human cystathionine beta-synthase (delta516-525) at 2.0 angstrom resolution

Summary for 4COO
Entry DOI10.2210/pdb4coo/pdb
DescriptorCYSTATHIONINE BETA-SYNTHASE, PROTOPORPHYRIN IX CONTAINING FE, ACETATE ION, ... (8 entities in total)
Functional Keywordslyase, methionine cycle, metabolic pathway, allosteric regulation, serine metabolism
Biological sourceHOMO SAPIENS (HUMAN)
Cellular locationCytoplasm : P35520
Total number of polymer chains2
Total formula weight127123.27
Authors
Primary citationMccorvie, T.J.,Kopec, J.,Hyung, S.,Fitzpatrick, F.,Feng, X.,Termine, D.,Strain-Damerell, C.,Vollmar, M.,Fleming, J.,Janz, J.M.,Bulawa, C.,Yue, W.W.
Inter-Domain Communication of Human Cystathionine Beta Synthase: Structural Basis of S-Adenosyl-L-Methionine Activation.
J.Biol.Chem., 289:36018-, 2014
Cited by
PubMed: 25336647
DOI: 10.1074/JBC.M114.610782
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2 Å)
Structure validation

217705

数据于2024-03-27公开中

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