4CI4
Structural basis for GL479 a dual Peroxisome Proliferator-Activated Receptor alpha agonist
Summary for 4CI4
| Entry DOI | 10.2210/pdb4ci4/pdb |
| Related | 4CI5 |
| Descriptor | PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR ALPHA, 2-methyl-2-[4-[2-[4-[(E)-phenyldiazenyl]phenoxy]ethyl]phenoxy]propanoic acid (3 entities in total) |
| Functional Keywords | transferase, dual agonist, ppar, nuclear receptor, gl479 |
| Biological source | HOMO SAPIENS (HUMAN) |
| Total number of polymer chains | 1 |
| Total formula weight | 31420.59 |
| Authors | Santos, J.C.,Bernardes, A.,Polikarpov, I. (deposition date: 2013-12-05, release date: 2014-12-24, Last modification date: 2023-12-20) |
| Primary citation | dos Santos, J.C.,Bernardes, A.,Giampietro, L.,Ammazzalorso, A.,De Filippis, B.,Amoroso, R.,Polikarpov, I. Different binding and recognition modes of GL479, a dual agonist of Peroxisome Proliferator-Activated Receptor alpha / gamma. J. Struct. Biol., 191:332-340, 2015 Cited by PubMed: 26185032DOI: 10.1016/j.jsb.2015.07.006 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.302 Å) |
Structure validation
Download full validation report
