4CDL
Crystal Structure of Retro-aldolase RA110.4-6 Complexed with Inhibitor 1-(6-methoxy-2-naphthalenyl)-1,3-butanedione
Summary for 4CDL
Entry DOI | 10.2210/pdb4cdl/pdb |
Descriptor | STEROID DELTA-ISOMERASE, (2E)-1-(6-methoxynaphthalen-2-yl)but-2-en-1-one (3 entities in total) |
Functional Keywords | isomerase, computational protein design, catalysis, directed evolution, protein engineering, enzyme engineering |
Biological source | PSEUDOMONAS PUTIDA |
Total number of polymer chains | 1 |
Total formula weight | 16383.60 |
Authors | Pinkas, D.M.,Studer, S.,Obexer, R.,Giger, L.,Gruetter, M.G.,Baker, D.,Hilvert, D. (deposition date: 2013-11-01, release date: 2014-11-12, Last modification date: 2023-12-20) |
Primary citation | Studer, S.,Obexer, R.,Giger, L.,Pinkas, D.M.,Gruetter, M.G.,Baker, D.,Hilvert, D. Active Site Plasticity of a Computationally Designed Retro-Aldolase Enzyme To be Published, |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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