4CD8

The structure of GH113 beta-mannanase AaManA from Alicyclobacillus acidocaldarius in complex with ManMIm

4CD8 の概要

• エントリーDOI: 10.2210/pdb4cd8/pdb
• 関連するPDBエントリー: 4CD4 4CD5 4CD6 4CD7
• 分子名称: ENDO-BETA-1,4-MANNANASE, (5R,6R,7S,8R)-5-(HYDROXYMETHYL)-5,6,7,8-TETRAHYDROIMIDAZO[1,2-A]PYRIDINE-6,7,8-TRIOL, beta-D-mannopyranose, ... (4 entities in total)
• 機能のキーワード: hydrolase, beta-mannosidase, mannosidase, glycoside hydrolase, gh26, gh113, cazy, enzyme-carbohydrate interaction, glycosidase inhibition, quantum mechanics, biocatalysis, conformation
• 由来する生物種: ALICYCLOBACILLUS ACIDOCALDARIUS
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 36723.31

構造登録者

Williams, R.J.,Iglesias-Fernandez, J.,Stepper, J.,Jackson, A.,Thompson, A.J.,Lowe, E.C.,White, J.M.,Gilbert, H.J.,Rovira, C.,Davies, G.J.,Williams, S.J. (登録日: 2013-10-30, 公開日: 2014-04-02, 最終更新日: 2023-12-20)

• 主引用文献: Williams, R.J.,Iglesias-Fernandez, J.,Stepper, J.,Jackson, A.,Thompson, A.J.,Lowe, E.C.,White, J.M.,Gilbert, H.J.,Rovira, C.,Davies, G.J.,Williams, S.J.; Combined Inhibitor Free-Energy Landscape and Structural Analysis Reports on the Mannosidase Conformational Coordinate.; Angew.Chem.Int.Ed.Engl., 53:1087-, 2014; PubMed: 24339341; DOI: 10.1002/ANIE.201308334

実験手法

X-RAY DIFFRACTION (1.47 Å)