4CD7

The structure of GH113 beta-mannanase AaManA from Alicyclobacillus acidocaldarius in complex with ManIFG and beta-1,4-mannobiose

Summary for 4CD7

• Entry DOI: 10.2210/pdb4cd7/pdb
• Related: 4CD4 4CD5 4CD6 4CD8
• Descriptor: ENDO-BETA-1,4-MANNANASE, beta-D-mannopyranose-(1-4)-alpha-D-mannopyranose, 5-HYDROXYMETHYL-3,4-DIHYDROXYPIPERIDINE, ... (5 entities in total)
• Functional Keywords: hydrolase, beta-mannosidase, mannosidase, glycoside hydrolase, gh26, gh113, cazy, enzyme-carbohydrate interaction, glycosidase inhibition, quantum mechanics, biocatalysis, conformation
• Biological source: ALICYCLOBACILLUS ACIDOCALDARIUS
• Total number of polymer chains: 2
• Total formula weight: 74025.17

Authors

Williams, R.J.,Iglesias-Fernandez, J.,Stepper, J.,Jackson, A.,Thompson, A.J.,Lowe, E.C.,White, J.M.,Gilbert, H.J.,Rovira, C.,Davies, G.J.,Williams, S.J. (deposition date: 2013-10-30, release date: 2014-04-02, Last modification date: 2023-12-20)

• Primary citation: Williams, R.J.,Iglesias-Fernandez, J.,Stepper, J.,Jackson, A.,Thompson, A.J.,Lowe, E.C.,White, J.M.,Gilbert, H.J.,Rovira, C.,Davies, G.J.,Williams, S.J.; Combined Inhibitor Free-Energy Landscape and Structural Analysis Reports on the Mannosidase Conformational Coordinate.; Angew.Chem.Int.Ed.Engl., 53:1087-, 2014; PubMed: 24339341; DOI: 10.1002/ANIE.201308334

Experimental method

X-RAY DIFFRACTION (1.65 Å)