4CCV
Crystal structure of histidine-rich glycoprotein N2 domain reveals redox activity at an interdomain disulfide bridge: Implications for the regulation of angiogenesis
Summary for 4CCV
Entry DOI | 10.2210/pdb4ccv/pdb |
Descriptor | HISTIDINE-RICH GLYCOPROTEIN, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLUTATHIONE, ... (5 entities in total) |
Functional Keywords | blood clotting, coagulation, cystatin, s-glutathionylation |
Biological source | ORYCTOLAGUS CUNICULUS (RABBIT) |
Total number of polymer chains | 1 |
Total formula weight | 14513.82 |
Authors | McMahon, S.A.,Kassaar, O.,Stewart, A.J.,Naismith, J.H. (deposition date: 2013-10-29, release date: 2014-02-19, Last modification date: 2020-07-29) |
Primary citation | Kassaar, O.,Mcmahon, S.A.,Thompson, R.,Botting, C.H.,Naismith, J.H.,Stewart, A.J. Crystal Structure of Histidine-Rich Glycoprotein N2 Domain Reveals Redox Activity at an Interdomain Disulfide Bridge: Implications for Angiogenic Regulation. Blood, 123:1948-, 2014 Cited by PubMed: 24501222DOI: 10.1182/BLOOD-2013-11-535963 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.93 Å) |
Structure validation
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