4CCV

Crystal structure of histidine-rich glycoprotein N2 domain reveals redox activity at an interdomain disulfide bridge: Implications for the regulation of angiogenesis

4CCV の概要

• エントリーDOI: 10.2210/pdb4ccv/pdb
• 分子名称: HISTIDINE-RICH GLYCOPROTEIN, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLUTATHIONE, ... (5 entities in total)
• 機能のキーワード: blood clotting, coagulation, cystatin, s-glutathionylation
• 由来する生物種: ORYCTOLAGUS CUNICULUS (RABBIT)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 14513.82

構造登録者

McMahon, S.A.,Kassaar, O.,Stewart, A.J.,Naismith, J.H. (登録日: 2013-10-29, 公開日: 2014-02-19, 最終更新日: 2020-07-29)

• 主引用文献: Kassaar, O.,Mcmahon, S.A.,Thompson, R.,Botting, C.H.,Naismith, J.H.,Stewart, A.J.; Crystal Structure of Histidine-Rich Glycoprotein N2 Domain Reveals Redox Activity at an Interdomain Disulfide Bridge: Implications for Angiogenic Regulation.; Blood, 123:1948-, 2014; PubMed: 24501222; DOI: 10.1182/BLOOD-2013-11-535963

実験手法

X-RAY DIFFRACTION (1.93 Å)