4CCJ

60S ribosomal protein L8 histidine hydroxylase (NO66) in apo form

4CCJ の概要

• エントリーDOI: 10.2210/pdb4ccj/pdb
• 関連するPDBエントリー: 2XDV 4BU2 4BXF 4CCK 4CCM 4CCN 4CCO 4DIQ
• 分子名称: BIFUNCTIONAL LYSINE-SPECIFIC DEMETHYLASE AND HISTIDYL-HYDROXYLASE NO66, 1,2-ETHANEDIOL (3 entities in total)
• 機能のキーワード: oxidoreductase, non-heme, iron-binding, dsbh, dioxygenase, jmjc domain, ribosome biogenesis, nuclear protein, rpl8, beta-hydroxylation, transcription and epigenetic regulation, signaling
• 由来する生物種: HOMO SAPIENS (HUMAN)
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 213150.97

構造登録者

Chowdhury, R.,Ge, W.,Clifton, I.J.,Schofield, C.J. (登録日: 2013-10-23, 公開日: 2014-05-14, 最終更新日: 2023-12-20)

• 主引用文献: Chowdhury, R.,Sekirnik, R.,Brissett, N.C.,Krojer, T.,Ho, C.H.,Ng, S.S.,Clifton, I.J.,Ge, W.,Kershaw, N.J.,Fox, G.C.,Muniz, J.R.C.,Vollmar, M.,Phillips, C.,Pilka, E.S.,Kavanagh, K.L.,von Delft, F.,Oppermann, U.,McDonough, M.A.,Doherty, A.J.,Schofield, C.J.; Ribosomal oxygenases are structurally conserved from prokaryotes to humans.; Nature, 510:422-426, 2014; PubMed: 24814345; DOI: 10.1038/nature13263

実験手法

X-RAY DIFFRACTION (2.15 Å)