4C83

Crystal Structure of the IgG2a LPT3 in complex with an 8-sugar inner core analogue of Neisseria meningitidis

Summary for 4C83

Entry DOI	10.2210/pdb4c83/pdb
Descriptor	LPT3 HEAVY CHAIN, LPT3 LIGHT CHAIN, 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-2)-L-glycero-alpha-D-manno-heptopyranose-(1-3)-[beta-D-glucopyranose-(1-4)]L-glycero-alpha-D-manno-heptopyranose-(1-5)-3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid, ... (5 entities in total)
Functional Keywords	immune system, lipooligosaccharides, antibodies, antigen-antibody complex
Biological source	MUS MUSCULUS (HOUSE MOUSE) More
Total number of polymer chains	4
Total formula weight	96516.96
Authors	Parker, M.J.,Gomery, K.,Richard, G.,Mackenzie, C.R.,Cox, A.D.,Richards, J.C.,Evans, S.V. (deposition date: 2013-09-29, release date: 2014-02-12, Last modification date: 2023-12-20)
Primary citation	Parker, M.J.,Gomery, K.,Richard, G.,Mackenzie, C.R.,Cox, A.D.,Richards, J.C.,Evans, S.V. Structural Basis for Selective Cross-Reactivity in a Bactericidal Antibody Against Inner Core Lipooligosaccharide from Neisseria Meningitidis. Glycobiology, 24:442-, 2014 Cited by PubMed: 24488440 DOI: 10.1093/GLYCOB/CWU009 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.69 Å)

Structure validation