4C7W

Crystal structure of Mouse Hepatitis virus strain S Hemagglutinin- esterase in complex with 4-O-acetylated sialic acid

Summary for 4C7W

• Entry DOI: 10.2210/pdb4c7w/pdb
• Related: 4C7L
• Descriptor: HEMAGGLUTININ-ESTERASE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (9 entities in total)
• Functional Keywords: hydrolase, receptor destroying, receptor binding
• Biological source: MURINE HEPATITIS VIRUS
• Total number of polymer chains: 2
• Total formula weight: 93568.91

Authors

Zeng, Q.H.,Huizinga, E.G. (deposition date: 2013-09-26, release date: 2013-10-16, Last modification date: 2023-12-20)

• Primary citation: Langereis, M.A.,Zeng, Q.,Heesters, B.A.,Huizinga, E.G.,De Groot, R.J.; The Murine Coronavirus Hemagglutinin-Esterase Receptor-Binding Site: A Major Shift in Ligand Specificity Through Modest Changes in Architecture.; Plos Pathog., 8:02492-, 2012; PubMed: 22291594; DOI: 10.1371/JOURNAL.PPAT.1002492

Experimental method

X-RAY DIFFRACTION (2.5 Å)