4C49

Reactive loop cleaved human CBG in complex with cortisol

Summary for 4C49

• Entry DOI: 10.2210/pdb4c49/pdb
• Related: 4C41
• Descriptor: CORTICOSTEROID-BINDING GLOBULIN, (11alpha,14beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione (3 entities in total)
• Functional Keywords: transport protein, corticosteroid binding globulin, serpin, hormone carrier
• Biological source: HOMO SAPIENS (HUMAN)
• Cellular location: Secreted: P08185
• Total number of polymer chains: 4
• Total formula weight: 167951.54

Authors

Chan, W.L.,Zhou, A.,Read, R.J. (deposition date: 2013-09-02, release date: 2014-10-01, Last modification date: 2023-12-20)

• Primary citation: Chan, W.L.,Zhou, A.,Read, R.J.; Role of Sa-Hd Loop Movement in Cortisol Release Mechanism of Cbg; To be Published,

Experimental method

X-RAY DIFFRACTION (2.7 Å)