4C3Z

Nucleotide-free crystal structure of nucleotide-binding domain 1 from human MRP1 supports a general-base catalysis mechanism for ATP hydrolysis.

4C3Z の概要

• エントリーDOI: 10.2210/pdb4c3z/pdb
• 分子名称: MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 1, SULFATE ION (3 entities in total)
• 機能のキーワード: transport protein, atp-binding cassette transporters, multidrug resistance protein 1, general-base mechanism
• 由来する生物種: HOMO SAPIENS (HUMAN)
• 細胞内の位置: Cell membrane ; Multi-pass membrane protein : P33527
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 29609.17

構造登録者

Chaptal, V.,Gueguen-Chaignon, V.,Magnard, S.,Falson, P.,Di Pietro, A.,Baubichon-Cortay, H. (登録日: 2013-08-28, 公開日: 2014-09-10, 最終更新日: 2023-12-20)

• 主引用文献: Chaptal, V.,Magnard, S.,Gueguen-Chaignon, V.,Falson, P.,Di Pietro, A.,Baubichon-Cortay, H.; Nucleotide-Free Crystal Structure of Nucleotide-Binding Domain 1 from Human Abcc1 Supports a 'General-Base Catalysis' Mechanism for ATP Hydrolysis.; Biochem.Pharm., 3:150-, 2014; DOI: 10.4172/2167-0501.1000150

実験手法

X-RAY DIFFRACTION (2.1 Å)