4C1E
Crystal structure of the metallo-beta-lactamase VIM-2 with D-captopril
Summary for 4C1E
Entry DOI | 10.2210/pdb4c1e/pdb |
Related | 4BZ3 4C09 4C1C 4C1D 4C1F 4C1G 4C1H |
Descriptor | BETA-LACTAMASE CLASS B VIM-2, SODIUM ION, 1-(3-MERCAPTO-2-METHYL-PROPIONYL)-PYRROLIDINE-2-CARBOXYLIC ACID, ... (6 entities in total) |
Functional Keywords | hydrolase, mbl. metallo-beta-lactamase, antibiotic resistance |
Biological source | PSEUDOMONAS AERUGINOSA |
Total number of polymer chains | 2 |
Total formula weight | 52490.11 |
Authors | Zollman, D.,Brem, J.,McDonough, M.A.,van Berkel, S.S.,Schofield, C.J. (deposition date: 2013-08-12, release date: 2014-08-27, Last modification date: 2023-12-20) |
Primary citation | Brem, J.,van Berkel, S.S.,Zollman, D.,Lee, S.Y.,Gileadi, O.,McHugh, P.J.,Walsh, T.R.,McDonough, M.A.,Schofield, C.J. Structural Basis of Metallo-beta-Lactamase Inhibition by Captopril Stereoisomers. Antimicrob. Agents Chemother., 60:142-150, 2015 Cited by PubMed: 26482303DOI: 10.1128/AAC.01335-15 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.399 Å) |
Structure validation
Download full validation report![Download](/newweb/media/icons/dl.png)
![Download](/newweb/media/icons/dl.png)