4BY3
Crystal structure of the dihydroorotase domain of human CAD in apo- form obtained recombinantly from E. coli.
Summary for 4BY3
| Entry DOI | 10.2210/pdb4by3/pdb |
| Descriptor | DIHYDROOROTASE, ZINC ION, FORMIC ACID, ... (4 entities in total) |
| Functional Keywords | hydrolase, de novo pyrimidine biosynthesis, amidohydrolase superfamily, metalloenzyme, zinc binding, histidinate anion |
| Biological source | HOMO SAPIENS (HUMAN) |
| Cellular location | Cytoplasm: P27708 |
| Total number of polymer chains | 1 |
| Total formula weight | 43361.76 |
| Authors | Ramon-Maiques, S.,Lallous, N.,Grande-Garcia, A. (deposition date: 2013-07-17, release date: 2014-05-28, Last modification date: 2023-12-20) |
| Primary citation | Grande-Garcia, A.,Lallous, N.,Diaz-Tejada, C.,Ramon-Maiques, S. Structure, Functional Characterization, and Evolution of the Dihydroorotase Domain of Human Cad. Structure, 22:185-, 2014 Cited by PubMed: 24332717DOI: 10.1016/J.STR.2013.10.016 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.73 Å) |
Structure validation
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