4BY2

SAS-4 (dCPAP) TCP domain in complex with a Proline Rich Motif of Ana2 (dSTIL) of Drosophila Melanogaster

Summary for 4BY2

• Entry DOI: 10.2210/pdb4by2/pdb
• Descriptor: ANASTRAL SPINDLE 2, SAS 4, 1,2-ETHANEDIOL (3 entities in total)
• Functional Keywords: structural protein, cpap, stil, microcephaly, mcph, centriole, tcp domain, extended beta sheet
• Biological source: DROSOPHILA MELANOGASTER (FRUIT FLY); More
• Total number of polymer chains: 3
• Total formula weight: 85880.26

Authors

Cottee, M.A.,Muschalik, N.,Wong, Y.L.,Johnson, C.M.,Johnson, S.,Andreeva, A.,Oegema, K.,Lea, S.M.,Raff, J.W.,van Breugel, M. (deposition date: 2013-07-17, release date: 2013-09-18, Last modification date: 2019-05-08)

• Primary citation: Cottee, M.A.,Muschalik, N.,Wong, Y.L.,Johnson, C.M.,Johnson, S.,Andreeva, A.,Oegema, K.,Lea, S.M.,Raff, J.W.,van Breugel, M.; Crystal structures of the CPAP/STIL complex reveal its role in centriole assembly and human microcephaly.; Elife, 2:e01071-e01071, 2013; PubMed: 24052813; DOI: 10.7554/eLife.01071

Experimental method

X-RAY DIFFRACTION (2.57 Å)