4BO0
Crystal structure of 3-oxoacyl-(acyl-carrier-protein) reductase (FabG) from Pseudomonas aeruginosa in complex with 1-(4-methoxy-1- methylindazol-3-yl)-3-(2-methoxyphenyl)urea at 2.4A resolution
Summary for 4BO0
Entry DOI | 10.2210/pdb4bo0/pdb |
Related | 4BNT 4BNU 4BNV 4BNW 4BNX 4BNY 4BNZ 4BO1 4BO2 4BO3 4BO4 4BO5 4BO6 4BO7 4BO8 4BO9 |
Descriptor | 3-OXOACYL-[ACYL-CARRIER-PROTEIN] REDUCTASE FABG, 1-(4-methoxy-1-methyl-indazol-3-yl)-3-(2-methoxyphenyl)urea, NICKEL (II) ION, ... (4 entities in total) |
Functional Keywords | oxidoreductase, rossmann fold, fatty acid biosynthesis |
Biological source | PSEUDOMONAS AERUGINOSA |
Total number of polymer chains | 4 |
Total formula weight | 113383.24 |
Authors | Cukier, C.D.,Schnell, R.,Lindqvist, Y.,Schneider, G. (deposition date: 2013-05-17, release date: 2013-09-18, Last modification date: 2023-12-20) |
Primary citation | Cukier, C.D.,Hope, A.,Elamin, A.,Moynie, L.,Schnell, R.,Schach, S.,Kneuper, H.,Singh, M.,Naismith, J.,Lindqvist, Y.,Gray, D.,Schneider, G. Discovery of an Allosteric Inhibitor Binding Site in 3-Oxo-Acyl-Acp Reductase from Pseudomonas Aeruginosa Acs Chem.Biol., 8:2518-, 2013 Cited by PubMed: 24015914DOI: 10.1021/CB4005063 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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