4BMK

Serine Palmitoyltransferase K265A from S. paucimobilis with bound PLP- Myriocin Aldimine

4BMK の概要

• エントリーDOI: 10.2210/pdb4bmk/pdb
• 分子名称: SERINE PALMITOYLTRANSFERASE, PYRIDOXAL-5'-PHOSPHATE, Decarboxylated Myriocin, ... (5 entities in total)
• 機能のキーワード: transferase-antibiotic complex, transferase, external aldimine, inhibitor, sphingolipids, natural product, antibiotic isp-1, transferase/antibiotic
• 由来する生物種: SPHINGOMONAS PAUCIMOBILIS
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 96081.49

構造登録者

Wadsworth, J.M.,Clarke, D.J.,McMahon, S.A.,Beattie, A.E.,Lowther, J.,Dunn, T.M.,Naismith, J.H.,Campopiano, D.J. (登録日: 2013-05-09, 公開日: 2013-09-04, 最終更新日: 2023-12-20)

• 主引用文献: Wadsworth, J.M.,Clarke, D.J.,Mcmahon, S.A.,Lowther, J.P.,Beattie, A.E.,Langridge-Smith, P.R.R.,Broughton, H.B.,Dunn, T.M.,Naismith, J.H.,Campopiano, D.J.; The Chemical Basis of Serine Palmitoyltransferase Inhibition by Myriocin.; J.Am.Chem.Soc., 135:14276-, 2013; PubMed: 23957439; DOI: 10.1021/JA4059876

実験手法

X-RAY DIFFRACTION (1.62 Å)