4BKL
Crystal structure of the arthritogenic antibody M2139 (Fab fragment) in complex with the triple-helical J1 peptide
Summary for 4BKL
Entry DOI | 10.2210/pdb4bkl/pdb |
Descriptor | M2139 FAB FRAGMENT HEAVY CHAIN, M2139 FAB FRAGMENT LIGHT CHAIN, J1 EPITOPE (3 entities in total) |
Functional Keywords | immune system, antibody, rheumatoid arthritis, collagen type ii |
Biological source | MUS MUSCULUS (HOUSE MOUSE) More |
Total number of polymer chains | 5 |
Total formula weight | 58596.88 |
Authors | Raposo, B.,Dobritzsch, D.,Ge, C.,Ekman, D.,Lindh, I.,Foerster, M.,Uysal, H.,Schneider, G.,Holmdahl, R. (deposition date: 2013-04-26, release date: 2014-02-05, Last modification date: 2023-12-20) |
Primary citation | Raposo, B.,Dobritzsch, D.,Ge, C.,Ekman, D.,Xu, B.,Lindh, I.,Forster, M.,Uysal, H.,Nandakumar, K.S.,Schneider, G.,Holmdahl, R. Epitope-Specific Antibody Response is Controlled by Immunoglobulin Vh Polymorphisms. J.Exp.Med., 211:405-, 2014 Cited by PubMed: 24534192DOI: 10.1084/JEM.20130968 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.25 Å) |
Structure validation
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