4BIM

CATALASE 3 FROM NEUROSPORA CRASSA IN TETRAGONAL FORM EXPOSES A MODIFIED TETRAMERIC ORGANIZATION

4BIM の概要

• エントリーDOI: 10.2210/pdb4bim/pdb
• 分子名称: CATALASE 3, PROTOPORPHYRIN IX CONTAINING FE (3 entities in total)
• 機能のキーワード: oxidoreductase, peroxidase, modified tetramer, large subunit catalase
• 由来する生物種: NEUROSPORA CRASSA
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 332674.51

構造登録者

Zarate-Romero, A.,Rudino-Pinera, E. (登録日: 2013-04-11, 公開日: 2013-04-24, 最終更新日: 2023-12-20)

主引用文献

Zarate-Romero, A.,Stojanoff, V.,Rojas-Trejo, S.P.,Hansberg, W.,Rudino-Pinera, E.
Conformational Stability and Crystal Packing: Polymorphism in Neurospora Crassa Cat-3
Acta Crystallogr.,Sect.F, 69:753-, 2013

PubMed Abstract: Polymorphism is frequently observed from different crystallization conditions. In proteins, the effect on conformational variability is poorly documented, with only a few reported examples. Here, three polymorphic crystal structures determined for a large-subunit catalase, CAT-3 from Neurospora crassa, are reported. Two of them belonged to new space groups, P1 and P43212, and a third structure belonged to the same space group, P212121, as the previously deposited 2.3 Å resolution structure (PDB entry 3ej6), but had a higher resolution (1.95 Å). Comparisons between these polymorphic structures highlight the conformational stability of tetrameric CAT-3 and reveal a distortion in the tetrameric structure that has not previously been described.

PubMed: 23832201
DOI: 10.1107/S1744309113013468

実験手法

X-RAY DIFFRACTION (2.95 Å)