4BIK
Structure of a disulfide locked mutant of Intermedilysin with human CD59
Summary for 4BIK
| Entry DOI | 10.2210/pdb4bik/pdb |
| Descriptor | INTERMEDILYSIN, CD59 GLYCOPROTEIN (2 entities in total) |
| Functional Keywords | complement, cholesterol dependent cytotoxin, immune system, membrane attack complex |
| Biological source | STREPTOCOCCUS INTERMEDIUS More |
| Cellular location | Cell membrane; Lipid-anchor, GPI-anchor: P13987 |
| Total number of polymer chains | 4 |
| Total formula weight | 136522.69 |
| Authors | Johnson, S.,Brooks, N.J.,Smith, R.A.G.,Lea, S.M.,Bubeck, D. (deposition date: 2013-04-10, release date: 2013-05-08, Last modification date: 2023-12-20) |
| Primary citation | Johnson, S.,Brooks, N.J.,Smith, R.A.G.,Lea, S.M.,Bubeck, D. Structural Basis for Recognition of the Pore- Forming Toxin Intermedilysin by Human Complement Receptor Cd59 Cell Rep., 3:1369-, 2013 Cited by PubMed: 23665225DOI: 10.1016/J.CELREP.2013.04.029 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (3.494 Å) |
Structure validation
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