4BIK

Structure of a disulfide locked mutant of Intermedilysin with human CD59

4BIK の概要

• エントリーDOI: 10.2210/pdb4bik/pdb
• 分子名称: INTERMEDILYSIN, CD59 GLYCOPROTEIN (2 entities in total)
• 機能のキーワード: complement, cholesterol dependent cytotoxin, immune system, membrane attack complex
• 由来する生物種: STREPTOCOCCUS INTERMEDIUS; 詳細
• 細胞内の位置: Cell membrane; Lipid-anchor, GPI-anchor: P13987
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 136522.69

構造登録者

Johnson, S.,Brooks, N.J.,Smith, R.A.G.,Lea, S.M.,Bubeck, D. (登録日: 2013-04-10, 公開日: 2013-05-08, 最終更新日: 2023-12-20)

• 主引用文献: Johnson, S.,Brooks, N.J.,Smith, R.A.G.,Lea, S.M.,Bubeck, D.; Structural Basis for Recognition of the Pore- Forming Toxin Intermedilysin by Human Complement Receptor Cd59; Cell Rep., 3:1369-, 2013; PubMed: 23665225; DOI: 10.1016/J.CELREP.2013.04.029

実験手法

X-RAY DIFFRACTION (3.494 Å)