4BE1
PFV intasome with inhibitor XZ-116
4BE1 の概要
エントリーDOI | 10.2210/pdb4be1/pdb |
関連するPDBエントリー | 2X6N 2X6S 2X74 2X78 4BAC 4BDY 4BDZ 4BE0 4BE2 |
分子名称 | INTEGRASE, 19 NUCLEOTIDE PREPROCESSED PFV DONOR DNA (NON-TRANSFERRED STRAND), 17 NUCLEOTIDE PREPROCESSED PFV DONOR DNA (TRANSFERRED STRAND), ... (10 entities in total) |
機能のキーワード | transferase-dna complex, protein-dna complex, dna integration, endonuclease, metal-binding, multifunctional enzyme, nuclease, nucleotidyltransferase, transferase, viral nucleoprotein, virion, dna-binding, zinc binding, hhcc motif, viral protein, recombination, inhibitor, recombination-inhibitor-dna complex, transferase/dna |
由来する生物種 | HUMAN SPUMARETROVIRUS 詳細 |
タンパク質・核酸の鎖数 | 4 |
化学式量合計 | 101064.21 |
構造登録者 | |
主引用文献 | Metifiot, M.,Maddali, K.,Johnson, B.C.,Hare, S.,Smith, S.J.,Zhao, X.Z.,Marchand, C.,Burke, T.R.,Hughes, S.H.,Cherepanov, P.,Pommier, Y. Activities, Crystal Structures and Molecular Dynamics of Dihydro-1H-Isoindole Derivatives, Inhibitors of HIV-1 Integrase. Acs Chem.Biol., 8:209-, 2013 Cited by PubMed: 23075516DOI: 10.1021/CB300471N 主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (2.71 Å) |
構造検証レポート
検証レポート(詳細版)をダウンロード