4BBH
Plasmodium vivax N-myristoyltransferase with a bound benzothiophene inhibitor
Summary for 4BBH
Entry DOI | 10.2210/pdb4bbh/pdb |
Related | 4A95 4B10 4B11 4B12 4B13 4B14 |
Descriptor | GLYCYLPEPTIDE N-TETRADECANOYLTRANSFERASE, DIMETHYL SULFOXIDE, 2-oxopentadecyl-CoA, ... (8 entities in total) |
Functional Keywords | transferase, myristoylation, malaria, inhibitor |
Biological source | PLASMODIUM VIVAX |
Total number of polymer chains | 3 |
Total formula weight | 139517.15 |
Authors | Rackham, M.D.,Brannigan, J.A.,Moss, D.K.,Yu, Z.,Wilkinson, A.J.,Holder, A.A.,Tate, E.W.,Leatherbarrow, R.J. (deposition date: 2012-09-23, release date: 2012-12-05, Last modification date: 2024-05-08) |
Primary citation | Rackham, M.D.,Brannigan, J.A.,Moss, D.K.,Yu, Z.,Wilkinson, A.J.,Holder, A.A.,Tate, E.W.,Leatherbarrow, R.J. Discovery of Novel and Ligand-Efficient Inhibitors of Plasmodium Falciparum and Plasmodium Vivax N-Myristoyltransferase. J.Med.Chem., 56:371-, 2013 Cited by PubMed: 23170970DOI: 10.1021/JM301474T PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.63 Å) |
Structure validation
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