4BAF

Hen egg-white lysozyme structure in complex with the europium tris- hydroxyethyltriazoledipicolinate complex at 1.51 A resolution.

4BAF の概要

• エントリーDOI: 10.2210/pdb4baf/pdb
• 関連するPDBエントリー: 3ZVQ 4A7D 4A8A 4A8B 4AGA 4AXT 4B0D 4B1A 4B49 4B4E 4B4I 4B4J 4BAD
• 分子名称: LYSOZYME C, EUROPIUM (III) ION, 4-(4-(2-hydroxyethyl)-1H-1,2,3-triazol-1-yl)pyridine-2,6-dicarboxylic acid, ... (7 entities in total)
• 機能のキーワード: hydrolase, click-chemistry, anomalous scattering, de novo phasing, lanthanide complex, dipicolinate
• 由来する生物種: GALLUS GALLUS (CHICKENS, BANTAM)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 15747.94

構造登録者

Talon, R.,Kahn, R.,Gautier, A.,Nauton, L.,Girard, E. (登録日: 2012-09-14, 公開日: 2012-11-14, 最終更新日: 2024-10-16)

主引用文献

Talon, R.,Nauton, L.,Canet, J.-L.,Kahn, R.,Girard, E.,Gautier, A.
Clicked Europium Dipicolinate Complexes for Protein X-Ray Structure Determination.
Chem.Commun.(Camb.), 48:11886-, 2012

PubMed Abstract: New trisdipicolinic acid-lanthanide complexes are reported as phasing agents for X-ray crystallography of proteins. It is demonstrated that CuAAC modifications allow protein co-crystallization with low concentration of lanthanide complexes leading to an accurate structure determination.

PubMed: 23123834
DOI: 10.1039/C2CC36982F

実験手法

X-RAY DIFFRACTION (1.507 Å)