4B7Y

Crystal structure of the MSL1-MSL2 complex

Summary for 4B7Y

Entry DOI	10.2210/pdb4b7y/pdb
Descriptor	MALE-SPECIFIC LETHAL 1 HOMOLOG, MALE-SPECIFIC LETHAL 2 HOMOLOG, ZINC ION (3 entities in total)
Functional Keywords	gene regulation, dosage compensation, chromatin
Biological source	HOMO SAPIENS (HUMAN) More
Cellular location	Nucleus: Q68DK7
Total number of polymer chains	4
Total formula weight	36385.55
Authors	Hallacli, E.,Lipp, M.,Georgiev, P.,Spielman, C.,Cusack, S.,Akhtar, A.,Kadlec, J. (deposition date: 2012-08-24, release date: 2013-02-06, Last modification date: 2023-12-20)
Primary citation	Hallacli, E.,Lipp, M.,Georgiev, P.,Spielman, C.,Cusack, S.,Akhtar, A.,Kadlec, J. Msl1-Mediated Dimerization of the Dosage Compensation Complex is Essential for Male X-Chromosome Regulation in Drosophila. Mol.Cell, 48:587-, 2012 Cited by PubMed: 23084835 DOI: 10.1016/J.MOLCEL.2012.09.014 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.25 Å)

Structure validation