4B4W

Crystal structure of Acinetobacter baumannii N5, N10- methylenetetrahydrofolate dehydrogenase-cyclohydrolase (FolD) complexed with NADP cofactor and an inhibitor

Summary for 4B4W

• Entry DOI: 10.2210/pdb4b4w/pdb
• Related: 4B4U 4B4V
• Descriptor: BIFUNCTIONAL PROTEIN FOLD, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, GLYCEROL, ... (6 entities in total)
• Functional Keywords: oxidoreductase
• Biological source: ACINETOBACTER BAUMANNII ATCC 19606
• Total number of polymer chains: 2
• Total formula weight: 66865.22

Authors

Eadsforth, T.C.,Maluf, F.V.,Hunter, W.N. (deposition date: 2012-08-01, release date: 2012-08-22, Last modification date: 2023-12-20)

• Primary citation: Eadsforth, T.C.,Maluf, F.V.,Hunter, W.N.; Acinetobacter Baumannii Fold Ligand Complexes; Potent Inhibitors of Folate Metabolism and a Re-Evaluation of the Ly374571 Structure.; FEBS J., 279:4350-, 2012; PubMed: 23050773; DOI: 10.1111/FEBS.12025

Experimental method

X-RAY DIFFRACTION (2 Å)