4B0P

Crystal structure of soman-aged human butyrylcholinesterase in complex with methyl 2-(pentafluorobenzyloxyimino)pyridinium

4B0P の概要

• エントリーDOI: 10.2210/pdb4b0p/pdb
• 関連するPDBエントリー: 1EHO 1EHQ 1KCJ 1P0I 1P0M 1P0P 1P0Q 1XLU 1XLV 1XLW 2J4C 2WID 2WIF 2WIG 2WIJ 2WIK 2WIL 2WSL 2XMB 2XMC 2XMD 2XMG 2XQF 2XQG 2XQI 2XQJ 2XQK 2Y1K 4AQD 4AXB 4B0O
• 分子名称: CHOLINESTERASE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCINE, ... (10 entities in total)
• 機能のキーワード: hydrolase, aging
• 由来する生物種: HOMO SAPIENS (HUMAN)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 62596.93

構造登録者

Wandhammer, M.,de Koning, M.,van Grol, M.,Noort, D.,Goeldner, M.,Nachon, F. (登録日: 2012-07-04, 公開日: 2012-08-29, 最終更新日: 2023-12-20)

• 主引用文献: Wandhammer, M.,De Koning, M.,Van Grol, M.,Loiodice, M.,Saurel, L.,Noort, D.,Goeldner, M.,Nachon, F.; A Step Toward the Reactivation of Aged Cholinesterases -Crystal Structure of Ligands Binding to Aged Human Butyrylcholinesterase; Chem.Biol.Interact, 203:19-, 2013; PubMed: 22922115; DOI: 10.1016/J.CBI.2012.08.005

実験手法

X-RAY DIFFRACTION (2.5 Å)