4AZ2
Human thrombin - inhibitor complex
Summary for 4AZ2
Entry DOI | 10.2210/pdb4az2/pdb |
Related | 4AYV 4AYY |
Descriptor | THROMBIN LIGHT CHAIN, THROMBIN HEAVY CHAIN, HIRUDIN-3A', ... (6 entities in total) |
Functional Keywords | hydrolase-inhibitor complex, hydrolase/inhibitor |
Biological source | HOMO SAPIENS (HUMAN) More |
Total number of polymer chains | 3 |
Total formula weight | 35210.23 |
Authors | Banner, D.W.,D'Arcy, A.,Winkler, F.K.,Hilpert, K. (deposition date: 2012-06-22, release date: 2012-08-15, Last modification date: 2024-05-01) |
Primary citation | Hilpert, K.,Ackermann, J.,Banner, D.W.,Gast, A.,Gubernator, K.,Hadvary, P.,Labler, L.,Muller, K.,Schmid, G.,Tschopp, T.B. Design and Synthesis of Potent and Highly Selective Thrombin Inhibitors. J.Med.Chem., 37:3889-, 1994 Cited by PubMed: 7966150DOI: 10.1021/JM00049A008 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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