4AXW

CRYSTAL STRUCTURE OF MOUSE CADHERIN-23 EC1-2 AND PROTOCADHERIN-15 EC1- 2, FORM I 2.2A.

Summary for 4AXW

• Entry DOI: 10.2210/pdb4axw/pdb
• Related: 2WBX 2WCP 2WD0 2WHV 4APX 4AQ8 4AQA 4AQE
• Descriptor: CADHERIN-23, PROTOCADHERIN-15, CALCIUM ION, ... (9 entities in total)
• Functional Keywords: cell adhesion, hearing, deafness, cadherin, cdh23, pcdh15, heterophilic
• Biological source: MUS MUSCULUS (HOUSE MOUSE); More
• Cellular location: Cell membrane; Single-pass type I membrane protein (By similarity): Q99PF4
• Total number of polymer chains: 2
• Total formula weight: 52195.71

Authors

Sotomayor, M.,Weihofen, W.,Gaudet, R.,Corey, D.P. (deposition date: 2012-06-14, release date: 2012-11-07, Last modification date: 2023-12-20)

• Primary citation: Sotomayor, M.,Weihofen, W.,Gaudet, R.,Corey, D.P.; Structure of a Force-Conveying Cadherin Bond Essential for Inner-Ear Mechanotransduction; Nature, 492:128-, 2012; PubMed: 23135401; DOI: 10.1038/NATURE11590

Experimental method

X-RAY DIFFRACTION (2.23 Å)