4AWM

Influenza strain pH1N1 2009 polymerase subunit PA endonuclease in complex with (-)-epigallocatechin gallate from green tea

4AWM の概要

• エントリーDOI: 10.2210/pdb4awm/pdb
• 関連するPDBエントリー: 4AVG 4AVL 4AVQ 4AWF 4AWG 4AWH 4AWK
• 分子名称: POLYMERASE PA, MANGANESE (II) ION, (2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl 3,4,5-trihydroxybenzoate, ... (4 entities in total)
• 機能のキーワード: hydrolase-inhibitor complex, hydrolase, manganese-dependent, pd...d-e...k superfamily, hydrolase/inhibitor
• 由来する生物種: INFLUENZA A VIRUS
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 23495.29

構造登録者

Kowalinski, E.,Zubieta, C.,Wolkerstorfer, A.,Szolar, O.H.,Ruigrok, R.W.,Cusack, S. (登録日: 2012-06-04, 公開日: 2012-08-22, 最終更新日: 2023-12-20)

• 主引用文献: Kowalinski, E.,Zubieta, C.,Wolkerstorfer, A.,Szolar, O.H.,Ruigrok, R.W.,Cusack, S.; Structural Analysis of Specific Metal Chelating Inhibitor Binding to the Endonuclease Domain of Influenza Ph1N1 (2009) Polymerase.; Plos Pathog., 8:2831-, 2012; PubMed: 22876177; DOI: 10.1371/JOURNAL.PPAT.1002831

実験手法

X-RAY DIFFRACTION (2.6 Å)