4AWF
Influenza strain pH1N1 2009 polymerase subunit PA endonuclease in complex with 2 4-dioxo-4-phenylbutanoic acid DPBA
Summary for 4AWF
Entry DOI | 10.2210/pdb4awf/pdb |
Related | 4AVG 4AVL 4AVQ 4AWG 4AWH 4AWK 4AWM |
Descriptor | POLYMERASE PA, MANGANESE (II) ION, 2-4-DIOXO-4-PHENYLBUTANOIC ACID, ... (4 entities in total) |
Functional Keywords | hydrolase-inhibitor complex, hydrolase, manganese-dependent, hydrolase/inhibitor |
Biological source | INFLUENZA A VIRUS |
Total number of polymer chains | 4 |
Total formula weight | 96965.34 |
Authors | Kowalinski, E.,Zubieta, C.,Wolkerstorfer, A.,Szolar, O.H.,Ruigrok, R.W.,Cusack, S. (deposition date: 2012-06-03, release date: 2012-08-22, Last modification date: 2023-12-20) |
Primary citation | Kowalinski, E.,Zubieta, C.,Wolkerstorfer, A.,Szolar, O.H.,Ruigrok, R.W.,Cusack, S. Structural Analysis of Specific Metal Chelating Inhibitor Binding to the Endonuclease Domain of Influenza Ph1N1 (2009) Polymerase. Plos Pathog., 8:2831-, 2012 Cited by PubMed: 22876177DOI: 10.1371/JOURNAL.PPAT.1002831 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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