4ASX

Crystal structure of Activin receptor type-IIA (ACVR2A) kinase domain in complex with dihydro-Bauerine C

4ASX の概要

• エントリーDOI: 10.2210/pdb4asx/pdb
• 分子名称: ACTIVIN RECEPTOR TYPE-2A, 7,8-bis(chloranyl)-9-methyl-3,4-dihydro-2H-pyrido[3,4-b]indol-1-one, 1,2-ETHANEDIOL, ... (4 entities in total)
• 機能のキーワード: transferase, protein kinase
• 由来する生物種: HOMO SAPIENS (HUMAN)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 74194.40

構造登録者

Williams, E.,Chaikuad, A.,Canning, P.,Kochan, G.,Mahajan, P.,Cooper, C.D.O.,Beltrami, A.,Krojer, T.,Pohl, B.,Bracher, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,von Delft, F.,Bullock, A. (登録日: 2012-05-03, 公開日: 2012-05-23, 最終更新日: 2023-12-20)

• 主引用文献: Williams, E.,Chaikuad, A.,Canning, P.,Mahajan, P.,Cooper, C.D.O.,Beltrami, A.,Krojer, T.,Huber, K.,Bracher, F.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Bullock, A.; Crystal Structure of Activin Receptor Type-Iia (Acvr2A) Kinase Domain in Complex with a Beta- Carboline Inhibitor; To be Published,

実験手法

X-RAY DIFFRACTION (2.05 Å)