4AQB

MBL-Ficolin Associated Protein-1, MAP-1 aka MAP44

Summary for 4AQB

Entry DOI	10.2210/pdb4aqb/pdb
Descriptor	MANNAN-BINDING LECTIN SERINE PROTEASE 1, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
Functional Keywords	blood clotting, mannan-binding protein, complement, ficolins, lectin complement pathway, mannose- binding lectin, mbl/ficolin associated protein-1, mbl/ficolin associated serine proteases, map1, map44
Biological source	HOMO SAPIENS (HUMAN)
Cellular location	Secreted: P48740
Total number of polymer chains	1
Total formula weight	43360.89
Authors	Skjoedt, M.O.,Roversi, P.,Hummelshoj, T.,Palarasah, Y.,Johnson, S.,Lea, S.M.,Garred, P. (deposition date: 2012-04-16, release date: 2012-08-08, Last modification date: 2023-12-20)
Primary citation	Skjoedt, M.O.,Roversi, P.,Hummelshoj, T.,Palarasah, Y.,Rosbjerg, A.,Johnson, S.,Lea, S.M.,Garred, P. Crystal Structure and Functional Characterization of the Complement Regulator Mannose-Binding Lectin (Mbl)/Ficolin-Associated Protein-1 (Map-1). J.Biol.Chem., 287:32913-, 2012 Cited by PubMed: 22854970 DOI: 10.1074/JBC.M112.386680 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (4.2 Å)

Structure validation