4AQB

MBL-Ficolin Associated Protein-1, MAP-1 aka MAP44

4AQB の概要

• エントリーDOI: 10.2210/pdb4aqb/pdb
• 分子名称: MANNAN-BINDING LECTIN SERINE PROTEASE 1, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• 機能のキーワード: blood clotting, mannan-binding protein, complement, ficolins, lectin complement pathway, mannose- binding lectin, mbl/ficolin associated protein-1, mbl/ficolin associated serine proteases, map1, map44
• 由来する生物種: HOMO SAPIENS (HUMAN)
• 細胞内の位置: Secreted: P48740
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 43360.89

構造登録者

Skjoedt, M.O.,Roversi, P.,Hummelshoj, T.,Palarasah, Y.,Johnson, S.,Lea, S.M.,Garred, P. (登録日: 2012-04-16, 公開日: 2012-08-08, 最終更新日: 2023-12-20)

• 主引用文献: Skjoedt, M.O.,Roversi, P.,Hummelshoj, T.,Palarasah, Y.,Rosbjerg, A.,Johnson, S.,Lea, S.M.,Garred, P.; Crystal Structure and Functional Characterization of the Complement Regulator Mannose-Binding Lectin (Mbl)/Ficolin-Associated Protein-1 (Map-1).; J.Biol.Chem., 287:32913-, 2012; PubMed: 22854970; DOI: 10.1074/JBC.M112.386680

実験手法

X-RAY DIFFRACTION (4.2 Å)