4ALK
Crystal structure of S. aureus FabI in complex with NADP and 5-ethyl- 2-phenoxyphenol
Summary for 4ALK
Entry DOI | 10.2210/pdb4alk/pdb |
Related | 4ALI 4ALJ 4ALL 4ALM 4ALN |
Descriptor | ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE [NADPH], NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 5-ETHYL-2-PHENOXYPHENOL, ... (5 entities in total) |
Functional Keywords | oxidoreductase, short-chain dehydrogenase/reductase superfamily, fatty acid biosynthesis, lipid synthesis, safabi, fabi |
Biological source | STAPHYLOCOCCUS AUREUS |
Total number of polymer chains | 8 |
Total formula weight | 257992.27 |
Authors | Schiebel, J.,Chang, A.,Tonge, P.J.,Kisker, C. (deposition date: 2012-03-04, release date: 2012-05-09, Last modification date: 2023-12-20) |
Primary citation | Schiebel, J.,Chang, A.,Lu, H.,Baxter, M.V.,Tonge, P.J.,Kisker, C. Staphylococcus Aureus Fabi: Inhibition, Substrate Recognition and Potential Implications for in Vivo Essentiality Structure, 20:802-, 2012 Cited by PubMed: 22579249DOI: 10.1016/J.STR.2012.03.013 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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