4ALK

Crystal structure of S. aureus FabI in complex with NADP and 5-ethyl- 2-phenoxyphenol

4ALK の概要

• エントリーDOI: 10.2210/pdb4alk/pdb
• 関連するPDBエントリー: 4ALI 4ALJ 4ALL 4ALM 4ALN
• 分子名称: ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE [NADPH], NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 5-ETHYL-2-PHENOXYPHENOL, ... (5 entities in total)
• 機能のキーワード: oxidoreductase, short-chain dehydrogenase/reductase superfamily, fatty acid biosynthesis, lipid synthesis, safabi, fabi
• 由来する生物種: STAPHYLOCOCCUS AUREUS
• タンパク質・核酸の鎖数: 8
• 化学式量合計: 257992.27

構造登録者

Schiebel, J.,Chang, A.,Tonge, P.J.,Kisker, C. (登録日: 2012-03-04, 公開日: 2012-05-09, 最終更新日: 2023-12-20)

• 主引用文献: Schiebel, J.,Chang, A.,Lu, H.,Baxter, M.V.,Tonge, P.J.,Kisker, C.; Staphylococcus Aureus Fabi: Inhibition, Substrate Recognition and Potential Implications for in Vivo Essentiality; Structure, 20:802-, 2012; PubMed: 22579249; DOI: 10.1016/J.STR.2012.03.013

実験手法

X-RAY DIFFRACTION (1.9 Å)