4AHJ
I46V - Angiogenin mutants and amyotrophic lateral sclerosis - a biochemical and biological analysis
Summary for 4AHJ
| Entry DOI | 10.2210/pdb4ahj/pdb |
| Related | 1A4Y 1ANG 1AWZ 1B1E 1B1I 1B1J 1H0D 1H52 1H53 1HBY 1K58 1K59 1K5A 1K5B 1UN3 1UN4 1UN5 2ANG 4AHD 4AHE 4AHF 4AHG 4AHH 4AHI 4AHJ 4AHK 4AHL 4AHM 4AHN |
| Descriptor | ANGIOGENIN, D(-)-TARTARIC ACID (3 entities in total) |
| Functional Keywords | hydrolase, amyotrophic, lateral sclerosis, neovascularisation |
| Biological source | HOMO SAPIENS (HUMAN) |
| Cellular location | Secreted: P03950 |
| Total number of polymer chains | 1 |
| Total formula weight | 14304.11 |
| Authors | Thiyagarajan, N.,Ferguson, R.,Saha, S.,Pham, T.,Subramanian, V.,Acharya, K.R. (deposition date: 2012-02-06, release date: 2012-10-10, Last modification date: 2023-12-20) |
| Primary citation | Thiyagarajan, N.,Ferguson, R.,Subramanian, V.,Acharya, K.R. Structural and Molecular Insights Into the Mechanism of Action of Human Angiogenin-Als Variants in Neurons. Nat.Commun., 3:1121-, 2012 Cited by PubMed: 23047679DOI: 10.1038/NCOMMS2126 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.032 Å) |
Structure validation
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