4A5A
Crystal structure of the C258S/C268S variant of Toxoplasma gondii nucleoside triphosphate diphosphohydrolase 3 (NTPDase3) in complex with magnesium and AMPPNP
Summary for 4A5A
Entry DOI | 10.2210/pdb4a5a/pdb |
Related | 4A57 4A59 4A5B |
Descriptor | NUCLEOSIDE-TRIPHOSPHATASE 1, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, MAGNESIUM ION (3 entities in total) |
Functional Keywords | hydrolase, ntpdase |
Biological source | TOXOPLASMA GONDII |
Cellular location | Secreted: Q27893 |
Total number of polymer chains | 4 |
Total formula weight | 272625.16 |
Authors | Krug, U.,Zebisch, M.,Straeter, N. (deposition date: 2011-10-24, release date: 2011-11-30, Last modification date: 2023-12-20) |
Primary citation | Krug, U.,Zebisch, M.,Krauss, M.,Straeter, N. Structural Insight Into the Activation Mechanism of Toxoplasma Gondii Nucleoside Triphosphate Diphosphohydrolases by Disulfide Reduction. J.Biol.Chem., 287:3051-, 2012 Cited by PubMed: 22130673DOI: 10.1074/JBC.M111.294348 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.85 Å) |
Structure validation
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