4A22

Structure of Mycobacterium tuberculosis fructose 1,6-bisphosphate aldolase bound to N-(4-hydroxybutyl)- glycolohydroxamic acid bis- phosphate

4A22 の概要

• エントリーDOI: 10.2210/pdb4a22/pdb
• 関連するPDBエントリー: 4A21
• 分子名称: FRUCTOSE-BISPHOSPHATE ALDOLASE, 4-{hydroxy[(phosphonooxy)acetyl]amino}butyl dihydrogen phosphate, SODIUM ION, ... (6 entities in total)
• 機能のキーワード: lyase, lyase-inhibitor complex
• 由来する生物種: MYCOBACTERIUM TUBERCULOSIS
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 148025.04

構造登録者

Coincon, M.,De la Paz Santangelo, M.,Gest, P.M.,Guerin, M.E.,Pham, H.,Ryan, G.,Puckett, S.E.,Spencer, J.S.,Gonzalez-Juarrero, M.,Daher, R.,Lenaerts, A.J.,Schnappinger, D.,Therisod, M.,Ehrt, S.,Jackson, M.,Sygusch, J. (登録日: 2011-09-21, 公開日: 2011-10-12, 最終更新日: 2018-11-21)

• 主引用文献: de la Paz Santangelo, M.,Gest, P.M.,Guerin, M.E.,Coincon, M.,Pham, H.,Ryan, G.,Puckett, S.E.,Spencer, J.S.,Gonzalez-Juarrero, M.,Daher, R.,Lenaerts, A.J.,Schnappinger, D.,Therisod, M.,Ehrt, S.,Sygusch, J.,Jackson, M.; Glycolytic and non-glycolytic functions of Mycobacterium tuberculosis fructose-1,6-bisphosphate aldolase, an essential enzyme produced by replicating and non-replicating bacilli.; J. Biol. Chem., 286:40219-40231, 2011; PubMed: 21949126; DOI: 10.1074/jbc.M111.259440

実験手法

X-RAY DIFFRACTION (1.9 Å)