4A1G
The crystal structure of the human Bub1 TPR domain in complex with the KI motif of Knl1
Summary for 4A1G
Entry DOI | 10.2210/pdb4a1g/pdb |
Descriptor | MITOTIC CHECKPOINT SERINE/THREONINE-PROTEIN KINASE BUB1, PROTEIN CASC5 (3 entities in total) |
Functional Keywords | cell cycle, transferase, spindle assembly checkpoint, mitosis, tpr repeat, knl1, kmn network |
Biological source | HOMO SAPIENS (HUMAN) More |
Cellular location | Nucleus: O43683 Q8NG31 |
Total number of polymer chains | 8 |
Total formula weight | 96132.22 |
Authors | Krenn, V.,Wehenkel, A.,Li, X.,Santaguida, S.,Musacchio, A. (deposition date: 2011-09-15, release date: 2012-02-29, Last modification date: 2023-12-20) |
Primary citation | Krenn, V.,Wehenkel, A.,Li, X.,Santaguida, S.,Musacchio, A. Structural Analysis Reveals Features of the Spindle Checkpoint Kinase Bub1-Kinetochore Subunit Knl1 Interaction. J.Cell Biol., 196:451-, 2012 Cited by PubMed: 22331848DOI: 10.1083/JCB.201110013 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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