4A0R

Structure of bifunctional DAPA aminotransferase-DTB synthetase from Arabidopsis thaliana bound to dethiobiotin (DTB).

Summary for 4A0R

• Entry DOI: 10.2210/pdb4a0r/pdb
• Related: 4A0F 4A0G 4A0H
• Descriptor: ADENOSYLMETHIONINE-8-AMINO-7-OXONONANOATE AMINOTRANSFERASE, PYRIDOXAL-5'-PHOSPHATE, L(+)-TARTARIC ACID, ... (5 entities in total)
• Functional Keywords: transferase, bio3-bio1, biotin synthesis
• Biological source: ARABIDOPSIS THALIANA (THALE CRESS)
• Cellular location: Mitochondrion (Potential): B0F481
• Total number of polymer chains: 2
• Total formula weight: 184077.36

Authors

Cobessi, D.,Dumas, R.,Pautre, V.,Meinguet, C.,Ferrer, J.L.,Alban, C. (deposition date: 2011-09-12, release date: 2012-06-13, Last modification date: 2012-10-31)

• Primary citation: Cobessi, D.,Dumas, R.,Pautre, V.,Meinguet, C.,Ferrer, J.L.,Alban, C.; Biochemical and Structural Characterization of the Arabidopsis Bifunctional Enzyme Dethiobiotin Synthetase-Diaminopelargonic Acid Aminotransferase: Evidence for Substrate Channeling in Biotin Synthesis.; Plant Cell, 24:1608-, 2012; PubMed: 22547782; DOI: 10.1105/TPC.112.097675

Experimental method

X-RAY DIFFRACTION (2.68 Å)