4A0Q

Activated Conformation of Integrin alpha1 I-Domain mutant

Summary for 4A0Q

Entry DOI	10.2210/pdb4a0q/pdb
Related	1PT6 1QC5 1QCY
Descriptor	INTEGRIN ALPHA-1, MAGNESIUM ION (3 entities in total)
Functional Keywords	integrin, cell adhesion
Biological source	HOMO SAPIENS (HUMAN)
Cellular location	Membrane; Single-pass type I membrane protein: P56199
Total number of polymer chains	2
Total formula weight	44775.06
Authors	Lahti, M.,Bligt, E.,Niskanen, H.,Parkash, V.,Brandt, A.-M.,Jokinen, J.,Patrikainen, P.,Kapyla, J.,Heino, J.,Salminen, T.A. (deposition date: 2011-09-12, release date: 2011-10-26, Last modification date: 2023-12-20)
Primary citation	Lahti, M.,Bligt, E.,Niskanen, H.,Parkash, V.,Brandt, A.M.,Jokinen, J.,Patrikainen, P.,Kapyla, J.,Heino, J.,Salminen, T.A. Structure of Collagen Receptor Integrin Aplha1I Domain Carrying the Activating Mutation E317A. J.Biol.Chem., 286:43343-, 2011 Cited by PubMed: 22030389 DOI: 10.1074/JBC.M111.261909 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation