4A0P

Crystal structure of LRP6P3E3P4E4

Summary for 4A0P

Entry DOI	10.2210/pdb4a0p/pdb
Descriptor	LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 6, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
Functional Keywords	signaling, lrp6, wnt signalling, wnt3a, dkk1, mesd
Biological source	HOMO SAPIENS (HUMAN)
Total number of polymer chains	1
Total formula weight	72812.04
Authors	Chen, S.,Malinauskas, T.,Aricescu, A.R.,Siebold, C.,Jones, E.Y. (deposition date: 2011-09-11, release date: 2011-10-26, Last modification date: 2023-12-20)
Primary citation	Chen, S.,Bubeck, D.,Macdonald, B.T.,Liang, W.X.,Mao, J.H.,Malinauskas, T.,Llorca, O.,Aricescu, A.R.,Siebold, C.,He, X.,Jones, E.Y. Structural and Functional Studies of Lrp6 Ectodomain Reveal a Platform for Wnt Signaling. Dev.Cell, 21:848-, 2011 Cited by PubMed: 22000855 DOI: 10.1016/J.DEVCEL.2011.09.007 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation